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Ubiquinone vs Ubiquinol
Ubiquinone and ubiquinol are two forms of the same CoQ10 molecule, and your body switches between them. Cardio Clear 7 lists ubiquinone, printed as ubidecarenone on the capsule. Ads often say ubiquinol absorbs better, but none of the sources we cite compares the two forms, so we cannot tell you one is better. The dose and the evidence matter more than the name.
Written by the Cardio Clear 7 research deskUpdated · 8 min read
01The names
What is the difference between ubiquinone and ubiquinol?
They are the same CoQ10 molecule in two states. One has given away electrons, and the other is holding them.
CoQ10 is a compound your body makes on its own. Cells use it to make energy and as an antioxidant (NCI PDQ - Coenzyme Q10). To do that job it keeps flipping between two forms.
- Ubiquinone is the oxidized form. It is ready to accept electrons. Ubidecarenone is another name for it, and the one often printed on labels.
- Ubiquinol is the reduced form. It is carrying electrons it can pass on.
Because the body converts one into the other, both names describe CoQ10. The real question for buyers is whether the form on the label changes anything you can notice. That is where the evidence gets thin.
02The capsule
Which form of CoQ10 is in Cardio Clear 7?
Ubiquinone. The brand's capsule photo shows "Co Q10" and "ubidecarenone" printed on the capsules, and ubidecarenone is the ubiquinone form.
The official store lists 100 mg of CoQ10 per capsule, with 80 mg shilajit extract and 10 mg PQQ disodium salt (Simple Promise store listing). The store listing does not use the word ubiquinol anywhere. No Supplement Facts panel image was supplied to us, so check the panel on your own bottle for the exact wording.
The store directions say one capsule a day with a meal (Simple Promise store listing). The brand's info page says with or without food (Cardio Clear 7 info page). CoQ10 is fat-soluble, so many people take it with a meal that has some fat. That is a sensible habit, not a tested rule for this product.
03What we can and cannot say
Is ubiquinol better absorbed than ubiquinone?
We cannot answer that from our sources, and we would rather say so than guess. Supplement ads often claim ubiquinol absorbs better. None of the 40 sources this site cites tests that claim.
| Question | What our sources say | Strength |
|---|---|---|
| Does the body make CoQ10 itself? | Yes; it uses it for cell growth and as an antioxidant (NCI PDQ - Coenzyme Q10) | Clear |
| Which form does Cardio Clear 7 list? | Ubiquinone, printed as ubidecarenone; 100 mg per capsule (Simple Promise store listing) | Clear |
| Does ubiquinol absorb better? | Not covered by any source we cite | Unknown |
| Did the blood pressure review compare forms? | Not reported in the summary we use (Zhao 2022 - CoQ10 BP dose-response) | Unknown |
| Did Q-SYMBIO report its form? | Not in the abstract or news report we use (Q-SYMBIO trial - JACC HF 2014) (Healio - Q-SYMBIO results report) | Unknown |
| Is one form safer? | No source we cite compares safety by form | Unknown |
A claim about absorption needs a study we have read and can link. Without one, the fair answer is "not shown by our sources". That is not proof the forms are equal. It is a gap in what we can verify.
04The research
What do the main CoQ10 studies tell a buyer?
They tell you about dose and about who was studied, more than about form. The bigger studies found the following for CoQ10 in general.
- Blood pressure
A 2022 review of 26 trials found systolic pressure about 4.77 mmHg lower, with the biggest effect near 100-200 mg a day (Zhao 2022 - CoQ10 BP dose-response). A Cochrane review of two small trials found no clinically significant effect (Cochrane - CoQ10 and hypertension).
- Heart failure
Q-SYMBIO gave 300 mg a day to 420 patients already on heart-failure treatment, for 2 years (Q-SYMBIO trial - JACC HF 2014). That is three times the amount in one Cardio Clear 7 capsule.
- Statin aches
Trials used 100-600 mg a day, with mixed results (Banach 2015 - CoQ10 statin myopathy) (Qu 2018 JAHA - CoQ10 statin symptoms).
Across these, the dose and the people studied explain more than the label name. A heart-failure patient on 300 mg is not the same as a healthy adult on 100 mg, whatever the form. For more on statins, read CoQ10 and statins.
Cardio Clear 7: from $31 a bottle30 capsules · 1, 3 or 6 bottles · free US shipping · 365-day money-back
See packs05Shopping
How should you compare CoQ10 labels?
Start with the amount, then the extras, then the proof. The form is one line among several.
Find the milligrams
Look for CoQ10 per serving and servings per day. Cardio Clear 7 is 100 mg in one capsule.
Read the form
Ubiquinone, ubidecarenone or ubiquinol. Note it, but do not pay a lot more for a name alone.
Check the other ingredients
Blends add things like shilajit and PQQ, which have their own thin research (Yan 2024 - PQQ review) (Examine - Shilajit evidence summary).
Ask for testing
A lab report you can read beats any badge. No lab report is published for Cardio Clear 7.
Our supplement facts page walks through the Cardio Clear 7 label line by line.
06Safety
Do the two forms have different side effects?
Our sources do not split side effects by form. For CoQ10 in general, mild trouble sleeping, nausea, diarrhea, upper stomach pain, dizziness and rash have been reported (NCCIH - Coenzyme Q10) (Mayo Clinic - Coenzyme Q10).
The interaction warnings apply to CoQ10 whatever its name. CoQ10 may make warfarin work less well, and bleeding has also been reported (Mayo Clinic - Coenzyme Q10) (MSKCC - Coenzyme Q10). It may also change how the body uses insulin (NCI PDQ - Coenzyme Q10).
Keep taking prescribed medicine; never stop or change it because of a supplement. If you take warfarin, tell your doctor before starting or switching any CoQ10 product.
07Bottom line
So which CoQ10 form should you choose?
Choose on dose, testing and price rather than form, since our sources cannot rank the two. Cardio Clear 7 uses ubiquinone at 100 mg, the low end of the blood pressure trials. One bottle is $59, or $31 a bottle in the 6-bottle pack, with a 365-day money-back guarantee (Cardio Clear 7 info page). The CoQ10 ingredient page has the full profile.
08FAQ
Ubiquinone vs ubiquinol: FAQ
Is ubidecarenone the same as ubiquinone?
Yes. Ubidecarenone is another name for ubiquinone, the oxidized form of CoQ10. The brand's capsule photo for Cardio Clear 7 shows ubidecarenone printed on the capsules, and the store lists 100 mg of CoQ10 per capsule (Simple Promise store listing).
Does Cardio Clear 7 use ubiquinol?
No. The capsule is printed with ubidecarenone, the ubiquinone form, and the store listing does not mention ubiquinol (Simple Promise store listing). Check the Supplement Facts panel on your own bottle, since no panel image was supplied to us.
Is ubiquinol worth the extra cost?
Our sources cannot say. None of the studies we cite compares ubiquinol with ubiquinone for absorption or results. Without that evidence, dose, testing and price are firmer ground for choosing a CoQ10 product than the form name.
Which form of CoQ10 is best for people over 50?
No source we cite answers that by age or form. The main CoQ10 studies report dose and the people studied, such as heart-failure patients on 300 mg a day (Q-SYMBIO trial - JACC HF 2014). Ask your doctor which dose fits your health and medicines.
Can the body turn ubiquinone into ubiquinol?
Yes, CoQ10 shifts between the two forms as it carries electrons in the cell. That is basic chemistry of the molecule. How well that conversion works in a given person, and whether it changes results, is not covered by the sources we cite.
Should I take CoQ10 with food?
The Cardio Clear 7 store says take one capsule a day with a meal (Simple Promise store listing); the info page says with or without food (Cardio Clear 7 info page). CoQ10 is fat-soluble, so a meal with some fat is a common habit, though not a tested rule for this product.
Is CoQ10 safe with warfarin in either form?
Ask your doctor first, whatever the form. CoQ10 may make warfarin work less well, raising clot risk, and bleeding has also been reported (Mayo Clinic - Coenzyme Q10) (MSKCC - Coenzyme Q10). Your doctor may want to check your INR more often.
09Who wrote this
Written and reviewed by
Pages built from the bottle, the official store listing, the brand info page and linked NIH, FDA, FTC and peer-reviewed sources.
Last updated . Read our editorial standards and how we check reviews. This website is run by a licensed U.S. retail desk, not by the manufacturer or by Simple Promise. We earn money when you buy through our order links.
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